产品货号：
Z32669
中文名称：
AEG-1/MTDH抗体
英文名称：
Anti-AEG-1/MTDH Antibody (Clone#OTI1E7)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-AEG-1/MTDH Antibody (Clone#OTI1E7) |
| 指标别名 | 3D3;3D3/LYRIC;AEG 1;AEG1;LYRIC;LYRIC/3D3;metadherin;Metastasis adhesion protein;MTDH;Protein LYRIC |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | MTDH |
| 克隆号 | OTI1E7 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG1 |
| 免疫原 | Human recombinant protein fragment corresponding to amino acids 70-582 of human MTDH (NP_848927)produced in SF9 cell. |
| 成分 | PBS (PH 7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
| 纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
| 背景资料 | MTDH (Metadherin),also known as protein LYRIC or astrocyte elevated gene-1 protein (AEG-1) is a protein that in humans is encoded by the MTDH gene.AEG-1 is involved in HIF-1alpha mediated angiogenesis.AEG-1 also interacts with SND1 and involved in RNA-induced silencing complex (RISC) and plays very important role in RISC and miRNA functions.AEG-1 induces an oncogene called Late SV40 factor (LSF/TFCP2) which is involved in thymidylate synthase (TS) induction and DNA biosynthesis synthesis.Late SV40 factor (LSF/TFCP2) enhances angiogenesis by transcriptionally up-regulating matrix metalloproteinase-9 (MMP9).AEG-1 acts as an oncogene in melanoma,malignant glioma,breast cancer and hepatocellular carcinoma.It is highly expressed in these cancers and helps in progression and development of these cancers.It is induced by c-Myc oncogene and plays very important role in anchorage independent growth of cancer cells. |
| Uniprot ID | Q86UE4 |
| 基因名全称 | metadherin |
| 蛋白名全称 | Protein LYRIC |
| 推荐稀释比 | Western blot (WB) 1:2000 Immunohistochemistry in paraffin section (IHC) 1:150 |
相关搜索：AEG-1/MTDH抗体，AEG-1抗体，MTDH单抗，Anti-AEG-1/MTDH Antibody (Clone#OTI1E7)